Five People You Must Know In The Canadian Pacific Cll Industry
페이지 정보
작성자 Dominique 작성일23-06-17 17:53 조회24회 댓글0건관련링크
본문
What is Multiple Myeloma?
Multiple myeloma also referred to as plasma cell cancer is caused by monoclonal cells that grow in bone marrow. It is a blood cancer that affects kidneys, bones and the nervous system.
The phase 3 trial randomly assigned patients with smoldering myeloma to receive lenalidomide and dexamethasone, with or without daratumumab. The International Myeloma Group's (IMWG) criteria defines smoldering MM.
What is Multiple Myeloma?
Multiple myeloma is a cancer that affects plasma cells. Plasma cells are formed in the bone marrow to fight infection. They produce antibodies which attack viruses and bacteria. These antibodies are produced in excess by multiple myeloma cancer cells. They can build up in the bones weakening them and causing pain. They can also clog the kidneys, making it difficult for them to filter blood.
Symptoms of multiple myeloma vary from person to. They may be mild or very severe. The symptoms could include fatigue, bone pain and loss of appetite. It is important to see a doctor if you have these symptoms. Your GP will examine you and conduct blood and urine tests. If they suspect multiple myeloma they will be taken to a hematologist.
Your doctor will determine if you have multiple myeloma based on the results of your blood and urine tests, bone marrow biopsy and imaging tests. A blood test to determine the amount and type of paraprotein is the most important test for diagnosing multiple myeloma. A MRI or CT scan of the head, spine or hips, ribs or the thigh can help identify areas of damaged bone. A positron emission tomography (PET) scan and FDG-PET scan are beneficial in detecting active cancer in the bone.
A rare side effect of multiple myeloma is hyperviscosity, which can lead to serious complications like oronasal bleeding, retinal hemorrhage, railroad Settlement and Railroad Settlement confusion. Plasmapheresis may be used to treat this condition.
Diagnosis
A lot of people with multiple myeloma are diagnosed by accident after having blood tests or X-rays to determine a different reason. Active monitoring is used by doctors to keep an eye on these patients. They don't require immediate treatment. They will seek treatment in the event of symptoms like kidney damage or bone pain.
To determine whether you're suffering from multiple myeloma, healthcare providers will collect a small amount of your blood and run an examination of your blood to check the levels of a protein called lactic dehydrogenase (LDH). This test will show if you have enough healthy blood cells to replace the damaged ones. If you don't, railroad settlement you may have cancer.
Your healthcare provider will also use imaging tests, such as a computed tomography (CT or CAT) scan or magnetic resonance imaging (MRI) and a positron emission tomography (PET) scan, to check for changes in your bones. They will also conduct a bone-marrow biopsy in order to check for abnormal plasmacytomas and the quantity of plasmacells in your bone-marrow.
Healthcare professionals will review the results of these tests and explain what they mean. If you're diagnosed with multiple myeloma your haematologist will recommend an appropriate treatment plan and keep track of your condition. They will prescribe medication to stop the myeloma growing or worsening, and to ease the symptoms. These medicines include lenalidomide, carfilzomib and pomalidomide.
Treatment
The aim of treatment is to reduce the amount of plasma cells and destroy the proteins they create. Chemotherapy drugs (often in combination) are used to do this. Radiation therapy can be directed to specific areas of the body or a large region, like the whole chest (called total-body irradiation). Steroids are frequently added to prevent the complications of chemotherapy and to help reduce the pain.
Bone-modifying medications can also be used to slow the loss bone. They can include thalidomide (Synvir, Thalomid) or lenalidomide (Revlimid, Kyprosis). In a study conducted in clinical trials, the addition of bortezomib proved to be effective.
In certain instances the doctor might recommend the transplantation of stem cells. There are 2 types of stem cell transplant - autologous and allogeneic. In allogeneic hematopoietic stem cell transplantation replacement blood stem cells are obtained from another person. Autologous stem cell transplantation occurs when stem cells are derived from bone marrow of the patient or their own blood.
Most people with multiple myeloma experience symptoms improve when they respond to treatment. It is important to keep up with your health care provider regularly and track your symptom changes. Your doctor(s) will check your calcium levels, creatinine levels (kidney function), hemoglobin levels (anemia) and bone scans to see how well you are responding to treatment.
Prevention
Although researchers haven't found an effective way to fight multiple myeloma yet, people are able to take steps to lower their risk. There are a variety of medicines that can help ease symptoms such as bone pain and anemia.
Most cases of myeloma occur in those over 60 years old. It is more common among blacks and non-Hispanic whites. A family history of myeloma, or other plasma cell diseases increases the chance of developing it. The risk of developing myeloma is increased by exposure to ionizing radio waves and certain substances however this is a rare cause.
In the past doctors treated patients suffering from myeloma with stem cell transplantation and chemotherapy. This involves using high-dose chemotherapy to kill cancerous cells and then replacing these with healthy stem cells taken from your body or given by a donor. After a period of time the new cells will replace diseased ones in your body. This treatment has led to greater survival and improved reaction to other treatments.
Researchers believe that understanding the molecular changes that occur when precursor conditions like monoclonal-gammopathy-of-undetermined significance (MGUS) progress to multiple myeloma may provide strategies to stop the progression. Researchers at OSUCCC James are conducting several studies to shed some light on the subject which include PCROWD and PROMISE.
Multiple myeloma also referred to as plasma cell cancer is caused by monoclonal cells that grow in bone marrow. It is a blood cancer that affects kidneys, bones and the nervous system.
The phase 3 trial randomly assigned patients with smoldering myeloma to receive lenalidomide and dexamethasone, with or without daratumumab. The International Myeloma Group's (IMWG) criteria defines smoldering MM.
What is Multiple Myeloma?
Multiple myeloma is a cancer that affects plasma cells. Plasma cells are formed in the bone marrow to fight infection. They produce antibodies which attack viruses and bacteria. These antibodies are produced in excess by multiple myeloma cancer cells. They can build up in the bones weakening them and causing pain. They can also clog the kidneys, making it difficult for them to filter blood.
Symptoms of multiple myeloma vary from person to. They may be mild or very severe. The symptoms could include fatigue, bone pain and loss of appetite. It is important to see a doctor if you have these symptoms. Your GP will examine you and conduct blood and urine tests. If they suspect multiple myeloma they will be taken to a hematologist.
Your doctor will determine if you have multiple myeloma based on the results of your blood and urine tests, bone marrow biopsy and imaging tests. A blood test to determine the amount and type of paraprotein is the most important test for diagnosing multiple myeloma. A MRI or CT scan of the head, spine or hips, ribs or the thigh can help identify areas of damaged bone. A positron emission tomography (PET) scan and FDG-PET scan are beneficial in detecting active cancer in the bone.
A rare side effect of multiple myeloma is hyperviscosity, which can lead to serious complications like oronasal bleeding, retinal hemorrhage, railroad Settlement and Railroad Settlement confusion. Plasmapheresis may be used to treat this condition.
Diagnosis
A lot of people with multiple myeloma are diagnosed by accident after having blood tests or X-rays to determine a different reason. Active monitoring is used by doctors to keep an eye on these patients. They don't require immediate treatment. They will seek treatment in the event of symptoms like kidney damage or bone pain.
To determine whether you're suffering from multiple myeloma, healthcare providers will collect a small amount of your blood and run an examination of your blood to check the levels of a protein called lactic dehydrogenase (LDH). This test will show if you have enough healthy blood cells to replace the damaged ones. If you don't, railroad settlement you may have cancer.
Your healthcare provider will also use imaging tests, such as a computed tomography (CT or CAT) scan or magnetic resonance imaging (MRI) and a positron emission tomography (PET) scan, to check for changes in your bones. They will also conduct a bone-marrow biopsy in order to check for abnormal plasmacytomas and the quantity of plasmacells in your bone-marrow.
Healthcare professionals will review the results of these tests and explain what they mean. If you're diagnosed with multiple myeloma your haematologist will recommend an appropriate treatment plan and keep track of your condition. They will prescribe medication to stop the myeloma growing or worsening, and to ease the symptoms. These medicines include lenalidomide, carfilzomib and pomalidomide.
Treatment
The aim of treatment is to reduce the amount of plasma cells and destroy the proteins they create. Chemotherapy drugs (often in combination) are used to do this. Radiation therapy can be directed to specific areas of the body or a large region, like the whole chest (called total-body irradiation). Steroids are frequently added to prevent the complications of chemotherapy and to help reduce the pain.
Bone-modifying medications can also be used to slow the loss bone. They can include thalidomide (Synvir, Thalomid) or lenalidomide (Revlimid, Kyprosis). In a study conducted in clinical trials, the addition of bortezomib proved to be effective.
In certain instances the doctor might recommend the transplantation of stem cells. There are 2 types of stem cell transplant - autologous and allogeneic. In allogeneic hematopoietic stem cell transplantation replacement blood stem cells are obtained from another person. Autologous stem cell transplantation occurs when stem cells are derived from bone marrow of the patient or their own blood.
Most people with multiple myeloma experience symptoms improve when they respond to treatment. It is important to keep up with your health care provider regularly and track your symptom changes. Your doctor(s) will check your calcium levels, creatinine levels (kidney function), hemoglobin levels (anemia) and bone scans to see how well you are responding to treatment.
Prevention
Although researchers haven't found an effective way to fight multiple myeloma yet, people are able to take steps to lower their risk. There are a variety of medicines that can help ease symptoms such as bone pain and anemia.
Most cases of myeloma occur in those over 60 years old. It is more common among blacks and non-Hispanic whites. A family history of myeloma, or other plasma cell diseases increases the chance of developing it. The risk of developing myeloma is increased by exposure to ionizing radio waves and certain substances however this is a rare cause.
In the past doctors treated patients suffering from myeloma with stem cell transplantation and chemotherapy. This involves using high-dose chemotherapy to kill cancerous cells and then replacing these with healthy stem cells taken from your body or given by a donor. After a period of time the new cells will replace diseased ones in your body. This treatment has led to greater survival and improved reaction to other treatments.
Researchers believe that understanding the molecular changes that occur when precursor conditions like monoclonal-gammopathy-of-undetermined significance (MGUS) progress to multiple myeloma may provide strategies to stop the progression. Researchers at OSUCCC James are conducting several studies to shed some light on the subject which include PCROWD and PROMISE.
댓글목록
등록된 댓글이 없습니다.
