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Multiple Myeloma and the kansas city southern railway myelodysplastic syndrome kansas city southern railway myelodysplastic syndrome kansas city southern railway aplastic anemia kansas city southern railway cll
Diesel exhaust is among the numerous hazardous chemicals railroad workers are exposed to. This means that they can get occupational cancers and other health issues.
Myeloma is a kind of blood cancer that affects plasma cells that are found in the bone marrow and produce antibodies. It can cause swelling, pain and other signs.
What is Multiple Myeloma?
Multiple myeloma (MMP) is a type of cancer of plasma cells, which form part of the immune system. Plasma cells create antibodies that aid the body to fight off infection. They are found mainly in bone marrow. It is the soft sponge-like tissue that creates blood within each bone. Multiple myeloma originates in plasma cells of the bone marrow. They then spread to other organs, like the kidneys and the spinal cord.
In multiple myeloma the cancerous plasma cell creates abnormal antibodies that accumulate in the kidneys or in other organs forming a mass known as a tumor. These tumors can consist of one cell or a cluster of cells. Tumors or lesions can cause weakness, fatigue as well as pain in the bones and tingling in the arms and leg. They also can cause anemia, high levels of calcium (hypercalcaemia) and issues with the bones.
There isn't a known cause of myeloma. However, certain factors increase the risk of developing it. These include age -- most people who develop myeloma are older than 60 and the disease is seen twice as frequently in black people as in whites -- and an ancestor's history of myelodysplastic syndrome or monoclonal gammopathy of undetermined significance (MGUS). People who have been exposed to radiation or chemicals such as pesticides or benzene are at a higher risk.
What is Multiple Myeloma Diagnosed?
Multiple myeloma is diagnosed or suspected only after a blood or urine test. Your GP will examine you for discomfort in your back, hips and ribs. This is referred to as an skeletal examination and could be a vital first step. You will also be asked if have other symptoms, for example, fatigue, decrease in appetite or bruising more easily than normal (a indication that plasma cells are preventing your body from producing enough platelets to stop bleeding).
The doctor will test the fluid around your lung for paraprotein. They will also examine your blood and bone marrow sample in order to check for abnormal proteins created by the myeloma cell. Your GP might recommend you to a specialist in blood disorders (a haematologist) for additional tests and scans.
X-rays and computed tomography (CT) scan, and magnetic resonance imaging (MRI) can aid in determining bone fractures caused by myeloma. Other tests may include a scan using positron emission tomography (PET) or FDG scan that helps to identify areas that are contaminated by cancerous plasma cells. Plasma exchange therapy (plasmapheresis), which removes the abnormal proteins from your body, can reduce their effect on kidneys, nerves and eyes.
What is the Treatment for Multiple Myeloma?
Typically, the symptoms of multiple myeloma improve as treatment progresses. Blood tests should be performed monthly to check for CRAB (Calcium levels and Renal/Kidney Functions, injury Settlement anemia and Bone Health) and any imaging scans, like Xrays or MRIs.
Most patients will get a combination of drugs as their induction and maintenance therapy. These include dexamethasone, lenalidomide, and an antibody monoclonal like elotuzumab (Empliciti) or daratumumab (Darzalex), that is associated with carfilzomib and pomalidomide.
The drugs slow myeloma and stop it from expanding. These drugs are taken by pill or through vein. There are also people who take bortezomib which is an alternative to Velcade. This drug can be combined with lenalidomide, dexamethasone, or doxorubicin cyclophosphamide.
Surgery is not a cure for multiple myeloma. However, it can be used to relieve certain symptoms such as spinal compression (from a fractured vertebra or plasmacytoma) or to remove large tumors that can hinder breathing.
The treatment for cancer can trigger physical adverse effects, like pain, as well as social and emotional adverse effects. Controlling these side effects is referred to as palliative medicine and is a crucial part of your overall treatment plan. The treatment team you choose to work with could include a general physician, a haematologist, a radiation oncologist or cancer nurse.
What are the potential side effects of multiple myeloma treatment?
Many of the drugs used to treat multiple myeloma have negative side effects. The degree and type of these side effects will depend on your health prior Injury Settlement to treatment, the specific chemo drugs you receive, as well as your individual reaction to them. In this video, hematologist-oncologist Adriana Rossi describes some of the side effects of common therapies for multiple myeloma.
The chemotherapy regimen for multiple myeloma comprises an amalgamation of several drugs. The chemo drugs kill cancer cells. Other medications, such as steroids, can be added to your chemo regimen to increase the likelihood of a positive outcome, or reduce the doses of chemotherapy you need. Steroids can result in a variety of adverse reactions, such as changes in appetite, diarrhea, elevated blood sugar levels (hyperglycemia) and a greater risk of getting infections.
Your medical team will design the treatment plan you need in accordance with the results of your tests, your stage of cancer, your symptoms, and your overall health. Your doctor will decide if you'd like to take part in a study that tests a new drug, a combination of standard treatments, or the best dosage of an existing medication.
Although it is not possible to treat myeloma multiplex treatment is a great way to manage symptoms and extend your life. Your medical team will create an individual plan that manages the pain, side effects and other signs to allow you to live life to the fullest. Palliative care is what this is.
Diesel exhaust is among the numerous hazardous chemicals railroad workers are exposed to. This means that they can get occupational cancers and other health issues.
Myeloma is a kind of blood cancer that affects plasma cells that are found in the bone marrow and produce antibodies. It can cause swelling, pain and other signs.
What is Multiple Myeloma?
Multiple myeloma (MMP) is a type of cancer of plasma cells, which form part of the immune system. Plasma cells create antibodies that aid the body to fight off infection. They are found mainly in bone marrow. It is the soft sponge-like tissue that creates blood within each bone. Multiple myeloma originates in plasma cells of the bone marrow. They then spread to other organs, like the kidneys and the spinal cord.
In multiple myeloma the cancerous plasma cell creates abnormal antibodies that accumulate in the kidneys or in other organs forming a mass known as a tumor. These tumors can consist of one cell or a cluster of cells. Tumors or lesions can cause weakness, fatigue as well as pain in the bones and tingling in the arms and leg. They also can cause anemia, high levels of calcium (hypercalcaemia) and issues with the bones.
There isn't a known cause of myeloma. However, certain factors increase the risk of developing it. These include age -- most people who develop myeloma are older than 60 and the disease is seen twice as frequently in black people as in whites -- and an ancestor's history of myelodysplastic syndrome or monoclonal gammopathy of undetermined significance (MGUS). People who have been exposed to radiation or chemicals such as pesticides or benzene are at a higher risk.
What is Multiple Myeloma Diagnosed?
Multiple myeloma is diagnosed or suspected only after a blood or urine test. Your GP will examine you for discomfort in your back, hips and ribs. This is referred to as an skeletal examination and could be a vital first step. You will also be asked if have other symptoms, for example, fatigue, decrease in appetite or bruising more easily than normal (a indication that plasma cells are preventing your body from producing enough platelets to stop bleeding).
The doctor will test the fluid around your lung for paraprotein. They will also examine your blood and bone marrow sample in order to check for abnormal proteins created by the myeloma cell. Your GP might recommend you to a specialist in blood disorders (a haematologist) for additional tests and scans.
X-rays and computed tomography (CT) scan, and magnetic resonance imaging (MRI) can aid in determining bone fractures caused by myeloma. Other tests may include a scan using positron emission tomography (PET) or FDG scan that helps to identify areas that are contaminated by cancerous plasma cells. Plasma exchange therapy (plasmapheresis), which removes the abnormal proteins from your body, can reduce their effect on kidneys, nerves and eyes.
What is the Treatment for Multiple Myeloma?
Typically, the symptoms of multiple myeloma improve as treatment progresses. Blood tests should be performed monthly to check for CRAB (Calcium levels and Renal/Kidney Functions, injury Settlement anemia and Bone Health) and any imaging scans, like Xrays or MRIs.
Most patients will get a combination of drugs as their induction and maintenance therapy. These include dexamethasone, lenalidomide, and an antibody monoclonal like elotuzumab (Empliciti) or daratumumab (Darzalex), that is associated with carfilzomib and pomalidomide.
The drugs slow myeloma and stop it from expanding. These drugs are taken by pill or through vein. There are also people who take bortezomib which is an alternative to Velcade. This drug can be combined with lenalidomide, dexamethasone, or doxorubicin cyclophosphamide.
Surgery is not a cure for multiple myeloma. However, it can be used to relieve certain symptoms such as spinal compression (from a fractured vertebra or plasmacytoma) or to remove large tumors that can hinder breathing.
The treatment for cancer can trigger physical adverse effects, like pain, as well as social and emotional adverse effects. Controlling these side effects is referred to as palliative medicine and is a crucial part of your overall treatment plan. The treatment team you choose to work with could include a general physician, a haematologist, a radiation oncologist or cancer nurse.
What are the potential side effects of multiple myeloma treatment?
Many of the drugs used to treat multiple myeloma have negative side effects. The degree and type of these side effects will depend on your health prior Injury Settlement to treatment, the specific chemo drugs you receive, as well as your individual reaction to them. In this video, hematologist-oncologist Adriana Rossi describes some of the side effects of common therapies for multiple myeloma.
The chemotherapy regimen for multiple myeloma comprises an amalgamation of several drugs. The chemo drugs kill cancer cells. Other medications, such as steroids, can be added to your chemo regimen to increase the likelihood of a positive outcome, or reduce the doses of chemotherapy you need. Steroids can result in a variety of adverse reactions, such as changes in appetite, diarrhea, elevated blood sugar levels (hyperglycemia) and a greater risk of getting infections.
Your medical team will design the treatment plan you need in accordance with the results of your tests, your stage of cancer, your symptoms, and your overall health. Your doctor will decide if you'd like to take part in a study that tests a new drug, a combination of standard treatments, or the best dosage of an existing medication.
Although it is not possible to treat myeloma multiplex treatment is a great way to manage symptoms and extend your life. Your medical team will create an individual plan that manages the pain, side effects and other signs to allow you to live life to the fullest. Palliative care is what this is.
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