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작성자 Stanton 작성일23-06-18 07:13 조회36회 댓글0건관련링크
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Multiple Myeloma and Aplastic Anemia
Aplastic anemia can affect blood and bone marrow (the sponge-like tissue inside bones which produces blood cells). Treatment involves medications that alter or inhibit the immune system (immunosuppressants) and an organ transplant using healthy donor blood stem cells.
A bone marrow transplant is a cure for severe and extremely severe anemias. It is recommended to perform the procedure with a matching sibling donor.
Causes
The bone the marrow (malathion) is a form of cancerous tissue. -foh- The sponge-like tissue (-dre) within the bones is responsible to make blood cells. These include red blood cells, white blood cells and platelets (PLA-tee-lets) which help fight infection and help the body to stop bleeding. Aplastic anemia is caused by bone marrow failing to produce enough new blood cells.
Aplastic anemia can have a variety of causes. Aplastic anemia can be caused by specific infections such as hepatitis and Epstein-Barr (the virus which causes mononucleosis). It can be caused by medicines or treatments like radiation therapy or chemotherapy to treat cancer. Sometimes, it is due to a genetic condition like Fanconi anemia or the ShwachmanDiamond syndrome.
Some people with aplastic ahememia are cured with bone Marrow transplants. However, the procedure is risky and is not a viable option for all. If you are unable to get an organ transplantation, or whose disease doesn't respond to transplants, may be treated with medicines that suppress the immune system. These medicines include antithymocyte globulin (ATG) and the cyclosporine. Eltrombopag, also referred to as Promacta is a different drug that can help people with severe anemia.
Anemia caused by multiple myeloma generally improves as you continue your treatment for myeloma aplastic anemia cancer. Your doctor might suggest supplements to your vitamin intake or prescribe medications to boost the production of red blood cells, such as epoetinalfa (Procrit or Epogen) and darbepoetin alfa (Aranesp). They can boost your quality of life while you receive multiple myeloma treatment.
Symptoms
Aplastic anemia can be caused by injury to your blood stem cells. These cells are mature blood cells that transform into red blood cells white blood cells, as well as platelets. The bone marrow does not produce enough of these cells if you have aplastic anemia. Other blood cells also may be damaged. This condition is sometimes called acquired aplastic angiopathy, but there are inherited or congenital bone marrow dysfunction syndromes that can manifest as aplastic anemia.
The symptoms vary based on the severity of your anemia and the cause. The most common symptoms are weakness and fatigue. They may be unable to fight off infections, or myeloma aplastic anemia they may become tired more easily. Some sufferers may experience headaches, dizziness or a rapid pulse. Other symptoms include a sensation of pins and needles (numbness) in the legs and arms, or bone pain.
A blood test can check for anemia that is aplastic. Your doctor will examine a sample of blood under a microscope. Your doctor might also recommend an aspiration of bone marrow or a biopsy. Your doctor will remove some of the fluid from your bones by using an instrument. The doctor will examine the marrow under a microscope to see whether there are any abnormal cells.
If your aplasticanemia isn't severe treatment may include medications and blood transfusions. You'll take medicines that suppress your immune system, like anti-thymocyte globulin (ATG) and Cyclosporine. Blood transfusions can aid in recovering your strength and fight off infection.
Diagnosis
Aplastic anemia is caused by damage to blood-forming cells that reside in the bone marrow. This causes anemia (low levels of red blood cells white blood cells, red blood cells and platelets). This can lead to fatigue, fatigue, and an increased chance of developing an infection. They also have a higher risk of developing multiple myeloma and other forms of cancer like leukemia or myelodysplastic syndrome.
A doctor can diagnose myeloma aplastic anemia through an blood test known as a complete blood count (CBC). This test checks for different kinds of blood cells in the body including red blood, white blood, and platelets. It also looks for abnormal clotting factors and proteins. If someone has a low or no blood cells count, the doctor may want to check for other causes.
Treatment for myeloma aplastic may include a bone marrow transplant, radiation therapy or medicines that suppress the immune system (immunosuppressants). These medicines, such as anti-thymocytes globulin, cyclosporine and Gengraf (Gengraf, Neoral) aid in preventing your immune system attacking healthy tissue in the bone marrow, or elsewhere in the body. Additionally, you can take erythropoietin supplements, such as Promacta (eltrombopag) that increase the number of red cells in the body.
Sometimes, doctors are not able to determine the cause of myeloma. In this instance, your doctor will try to rule out other conditions like hepatitis or paroxysmal nocturnal hemoglobinuria that may have similar symptoms.
Treatment
Aplastic anemia can be treated with blood transfusions in certain cases to increase the number healthy blood cells, including platlet and red. Your doctor could also remove your spleen (splenectomy) to stop it from taking out too many worn-out blood cells, which can cause anemia.
You may require a medicine that helps your bone marrow produce more blood cells. Examples include erythropoietin and the granulocyte colony-stimulating factor. These medicines are copies of substances that your body naturally produces. You may also require medication to treat or avoid infections that may occur when your blood count is low. Your doctor may prescribe antibiotics or other medicines that eliminate bacteria.
Your doctor may try to control the autoimmune response that is damaging your bone marrow by giving you medications known as immunosuppressive agents. The standard therapy is antithymocyte globulin, cyclosporine or, in some settings combination with eltrombopag (Promacta).
Acute myeloidleukemia and other rare blood cancers can be observed in a bone marrow biopsy. These types of leukemias are typically associated with hypercellular bone marrow as well as peripheral blood cytopenias.
Aplastic anemia can affect blood and bone marrow (the sponge-like tissue inside bones which produces blood cells). Treatment involves medications that alter or inhibit the immune system (immunosuppressants) and an organ transplant using healthy donor blood stem cells.
A bone marrow transplant is a cure for severe and extremely severe anemias. It is recommended to perform the procedure with a matching sibling donor.
Causes
The bone the marrow (malathion) is a form of cancerous tissue. -foh- The sponge-like tissue (-dre) within the bones is responsible to make blood cells. These include red blood cells, white blood cells and platelets (PLA-tee-lets) which help fight infection and help the body to stop bleeding. Aplastic anemia is caused by bone marrow failing to produce enough new blood cells.
Aplastic anemia can have a variety of causes. Aplastic anemia can be caused by specific infections such as hepatitis and Epstein-Barr (the virus which causes mononucleosis). It can be caused by medicines or treatments like radiation therapy or chemotherapy to treat cancer. Sometimes, it is due to a genetic condition like Fanconi anemia or the ShwachmanDiamond syndrome.
Some people with aplastic ahememia are cured with bone Marrow transplants. However, the procedure is risky and is not a viable option for all. If you are unable to get an organ transplantation, or whose disease doesn't respond to transplants, may be treated with medicines that suppress the immune system. These medicines include antithymocyte globulin (ATG) and the cyclosporine. Eltrombopag, also referred to as Promacta is a different drug that can help people with severe anemia.
Anemia caused by multiple myeloma generally improves as you continue your treatment for myeloma aplastic anemia cancer. Your doctor might suggest supplements to your vitamin intake or prescribe medications to boost the production of red blood cells, such as epoetinalfa (Procrit or Epogen) and darbepoetin alfa (Aranesp). They can boost your quality of life while you receive multiple myeloma treatment.
Symptoms
Aplastic anemia can be caused by injury to your blood stem cells. These cells are mature blood cells that transform into red blood cells white blood cells, as well as platelets. The bone marrow does not produce enough of these cells if you have aplastic anemia. Other blood cells also may be damaged. This condition is sometimes called acquired aplastic angiopathy, but there are inherited or congenital bone marrow dysfunction syndromes that can manifest as aplastic anemia.
The symptoms vary based on the severity of your anemia and the cause. The most common symptoms are weakness and fatigue. They may be unable to fight off infections, or myeloma aplastic anemia they may become tired more easily. Some sufferers may experience headaches, dizziness or a rapid pulse. Other symptoms include a sensation of pins and needles (numbness) in the legs and arms, or bone pain.
A blood test can check for anemia that is aplastic. Your doctor will examine a sample of blood under a microscope. Your doctor might also recommend an aspiration of bone marrow or a biopsy. Your doctor will remove some of the fluid from your bones by using an instrument. The doctor will examine the marrow under a microscope to see whether there are any abnormal cells.
If your aplasticanemia isn't severe treatment may include medications and blood transfusions. You'll take medicines that suppress your immune system, like anti-thymocyte globulin (ATG) and Cyclosporine. Blood transfusions can aid in recovering your strength and fight off infection.
Diagnosis
Aplastic anemia is caused by damage to blood-forming cells that reside in the bone marrow. This causes anemia (low levels of red blood cells white blood cells, red blood cells and platelets). This can lead to fatigue, fatigue, and an increased chance of developing an infection. They also have a higher risk of developing multiple myeloma and other forms of cancer like leukemia or myelodysplastic syndrome.
A doctor can diagnose myeloma aplastic anemia through an blood test known as a complete blood count (CBC). This test checks for different kinds of blood cells in the body including red blood, white blood, and platelets. It also looks for abnormal clotting factors and proteins. If someone has a low or no blood cells count, the doctor may want to check for other causes.
Treatment for myeloma aplastic may include a bone marrow transplant, radiation therapy or medicines that suppress the immune system (immunosuppressants). These medicines, such as anti-thymocytes globulin, cyclosporine and Gengraf (Gengraf, Neoral) aid in preventing your immune system attacking healthy tissue in the bone marrow, or elsewhere in the body. Additionally, you can take erythropoietin supplements, such as Promacta (eltrombopag) that increase the number of red cells in the body.
Sometimes, doctors are not able to determine the cause of myeloma. In this instance, your doctor will try to rule out other conditions like hepatitis or paroxysmal nocturnal hemoglobinuria that may have similar symptoms.
Treatment
Aplastic anemia can be treated with blood transfusions in certain cases to increase the number healthy blood cells, including platlet and red. Your doctor could also remove your spleen (splenectomy) to stop it from taking out too many worn-out blood cells, which can cause anemia.
You may require a medicine that helps your bone marrow produce more blood cells. Examples include erythropoietin and the granulocyte colony-stimulating factor. These medicines are copies of substances that your body naturally produces. You may also require medication to treat or avoid infections that may occur when your blood count is low. Your doctor may prescribe antibiotics or other medicines that eliminate bacteria.
Your doctor may try to control the autoimmune response that is damaging your bone marrow by giving you medications known as immunosuppressive agents. The standard therapy is antithymocyte globulin, cyclosporine or, in some settings combination with eltrombopag (Promacta).
Acute myeloidleukemia and other rare blood cancers can be observed in a bone marrow biopsy. These types of leukemias are typically associated with hypercellular bone marrow as well as peripheral blood cytopenias.
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