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작성자 Cynthia 작성일23-06-18 14:32 조회13회 댓글0건

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Acute Myeloid Leukemia Injury

The cancer starts in blood stem cells and quickly spreads to blood and bone-marrow. The cancer causes too many immature white blood cells to be made, crowding out healthy cells. The leukemia cells are also able to invade other areas of the body like the spleen and liver. They can also cause tumors in the central nervous system (brain and spine cord).

Treatment is contingent on whether AML has spread and what the subtype is. It may include chemotherapy, radiation therapy or other drugs to treat different types of cancer.

Signs and symptoms

The blood-forming cells which make up the bone marrow and blood (leukemia cells) become out of control. They develop into abnormal white blood cells that don't become healthy platelets or red blood cells. These cancerous blood-forming cells obstruct normal blood-forming ones, creating problems with the immune system and elsewhere in the body.

These symptoms can be sudden within a few days or weeks. They may include fatigue, fever, bruising or bleeding and sometimes vomiting. A bone marrow biopsies and blood tests indicate an abnormal white cell count.

If the cancer spreads to the brain, it could cause seizures, headaches or vision and balance problems. It can also affect the lungs and heart. It is often difficult to determine whether leukemia is located in the brain or in the chest. Doctors perform the test called a lumbar prick to take a sample of cerebrospinal fluid (CSF) to analyze.

A lumbar puncture is the process of inserting an needle into the lower part of the spine. It is typically done with the help of an anesthesiologist, but patients can opt to have it done by a doctor or nurse. CSF tests can tell if the leukemia is in the spine, or has metastasized, to the brain and other parts of the body.

Diagnosis

Leukemia is a condition that occurs when a bone marrow-derived cell has changes (mutations) in its DNA. DNA gives a cell its instructions on how to grow and die. When a bone-marrow's DNA is altered and is not able to produce normal white blood cells or other healthy cells. The abnormal cells build up and block healthy cells, Acute myeloid Leukemia railroad cancer settlements which means the body isn't able to fight infections. Myeloblasts are a type of blood cell that is immature known as myeloblasts. They also have a very low percentage of healthy red blood cells and platelets.

Leukemia is diagnosed by an examination of the body and health history. The doctor will examine the patient for signs of cancer, such as a fever or a lump in the skin. The doctor will also ask the patient about their previous ailments and treatments.

Blood tests can indicate how well organs are functioning and the levels of certain chemicals in the blood. A blood sample can be checked for the number of normal white blood cells and red blood cells and platelets. A special test will look for chromosomes inside the bone marrow.

Other tests can help identify complications caused by leukemia and its treatment. These include changes in the skin color or a tumor on the chest, or a problem with the spinal cord or brain.

Treatment

In this type of leukemia, the immature blood cells multiply and engorge healthy blood cells. It affects hematopoietic stem cells which are blood-forming cells in bone the marrow (the soft, spongy tissue within long bones). Hematopoietic stems cells develop or mature into red blood cells white blood cells and platelets. The term "Acute Myeloid Leukemia Railroad Cancer Settlements" signifies that it develops rapidly. This kind of leukemia is also known as acute myeloid leukemia railroad lawsuits myelogenous Leukemia or acute myeloid leukemia railroad injury myeloblastic leukemia or acute myeloid leukemia cancer granulocytic leukemia.

Doctors diagnose leukemia through examining symptoms and the results of certain tests. They may also do imaging studies, like X-rays, CT scans, and MRI, to find out whether the leukemia has spread to the chest or the brain. Other tests in the lab like flow-cytometry assist doctors in determining the type and subtypes of leukemia. This is important since treatment differs based on the type.

People with AML are at risk of complications. Complications may be caused by leukemia or its treatments like chemotherapy and radiotherapy. These include recurrent infection, anemia (low amount of red blood cells) and bleeding issues easily bruising and lower numbers (neutropenia and thrombocytopenia) of blood-forming cells. There are some who develop an alopecia that appears as tiny flat spots within or on the skin. Additionally, they may have swollen or enlarged lymph nodes, or spleens (hepatomegaly or splenomegaly). Certain people experience changes in their thinking and behavior or mood swings that could be due to the spread of the disease or effects of chemotherapy.

The following is a list of preventions.

AML develops when stem cells or blood cells in the bone marrow (the soft, spongy material in certain bones) produce a high amount of immature white blood cells. These cells aren't normal, and they don't fight infections as they should. They also crowd out healthy blood-producing cell. This can lead to an absence of different kinds of healthy blood cells.

The risk of AML increases with age. Smoking, radiation exposure, and previous chemotherapy treatments and certain genetic mutations like a all-trans retinoic Acid (ATRA) (Alkeran) or Enasidenib can increase the risk.

Doctors treat AML with a drug that targets specific proteins involved in the cancerous cell growth. This includes drugs such as azacitidine, decitabine, and midostaurin. Radiation therapy involves the use of high-energy x rays or particles to kill cancerous cells. Doctors may also give medicines to stop the cancer from returning, called recurrence, after an individual is in recovery. These include nilotinib, (Imatinib) and avastin, (Rydapt). A patient can also get newer medications being tested in clinical trials. A transplant of bone marrow with healthy stem cells from the hematopoietic system is another method to treat AML. These stem cells can be donated by an outside source or taken from the bone marrow of a patient.

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