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작성자 Madeline 작성일23-06-18 16:25 조회54회 댓글0건

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Esophageal Cancer Injury

Acid reflux in the stomach can cause damage to the internal lining of the esophagus. This can result in cancer, also known as squamous cell cancer (SCC).

Smoking and drinking excessively increase the chance of developing esophageal cancer. So does being overweight.

A rise in consumption of red meat has been associated with an increased risk of cancer of the esophagus likely due to cooking techniques and the higher heme iron content.

Symptoms

Inhaling or consuming caustic chemicals can cause severe chemical burns, known as squamous cell cancer, in the linings of the esophagus. Squamous cell cancer in the esophagus can be caused by ingesting Lye. However other caustic substances like pool cleaners hair relaxers and laundry detergents can also cause damage to the lining. These chemicals can create scar tissue in the region of injury, leading to a narrowing of esophagus. Around half of people with an esophagus stricture develop squamous cell cancer in this area for many years later, Esophageal cancer railroad cancer settlements or even decades after.

The esophagus (or esophagus) is a long, tube-like structure that runs from the throat to the stomach. It transports food that has been swallowed and liquids from the mouth to the stomach. The esophagus is home to cells that secrete a mucus. This helps protect the lining. The cancer that develops within these cells could spread to other tissues or distant parts of the human body.

Most esophageal carcinomas do not show symptoms until they are advanced. Dysphagia is a frequent sign of a tumor's growth blocking the passageway of food. People who experience these symptoms should consult their doctor however, it is important to remember that they could also be caused by other health issues.

Diagnosis

The esophagus extends from the throat down to the stomach. Its lining releases mucus which helps to lubricate it and protects it from damage. The esophagus is a cancerous organ when abnormal cells develop out of control and destroy surrounding tissue, or spread to other organs of the body.

Esophageal cancer occurs most often in the lining of the esophagus, however, it may also be found in the muscle layer or the outer wall of the esophagus. Squamous cell cancer is the most frequent type of esophageal cancer. It develops from thin, flat cells that line many organs, including the esophagus. Other types of esophageal cancer, such as lymphoma and adenocarcinoma, can sometimes be detected in conjunction with it.

Chronic heartburn can increase the chances of developing esophageal cancer. When acid from the stomach flows into the esophagus over and over again and causes a condition known as gastroesophageal acid reflux disease, also known as GERD it can damage the tissue of the esophagus and lead to the growth of gland cells which are more likely develop cancer.

Doctors can identify esophageal carcinoma by looking at your throat and esophagus as conducting other tests. These include an esophagogastroduodenoscopy (EGD) -- during this test, a doctor inserts a flexible tube down your throat into the esophagus and stomach to check the tissue for abnormal cells. The doctor may also take an esophagus sample for analysis (biopsy).

Treatment

Cancer begins in the cells that line your esophagus. The most commonly diagnosed esophageal tumor is called squamous cell carcinoma. It can be found in the mucosa, thin muscle layer, or the thicker muscle layers of the esophagus. Adenocarcinoma is yet another form of esophageal carcinoma. It is a result of gland cells and usually occurs in the lower esophagus, close to the stomach. The cancer may develop in other parts of your body, like the lungs or liver.

The first step to determine your treatment is to find out how far the esophageal cancer has been able to spread. To do this, your doctor could conduct an imaging test. A harmless liquid with a chalky taste called barium is swallowed, and then X-rays are taken of your esophagus. This enables your doctor to examine the stomach's lining. Additional tests, such as a computed-tomography scan (CT) with contrast, positron emission tomography scan (PET) and thoracoscopy, can determine if cancer has developed.

Surgery, chemotherapy and radiotherapy are the most effective treatments for esophageal cancer. Certain patients also benefit from medical procedures such as endoscopic mucosal removal (EMR) and cryotherapy. A team approach is essential in treating esophageal cancer. At UVA, our gastroenterologists as well as specialists in radiation oncology and medical oncology collaborate to ensure you receive the best treatment for your specific condition.

Prevention

Ingestable chemicals, such as lye can increase the risk for esophageal carcinoma by altering or damaging cells in the lining. In general these changes are more likely to lead to squamous cell carcinoma than adenocarcinoma. Squamous cell cancers are more prevalent in males and older people. Alcohol and tobacco use are modifiable risk factor for esophageal carcinoma.

Drinking heavily is associated with squamous cell cancer of the esophagus. These risk factors cannot be easily changed, but you can reduce the risk of developing esophageal cancer railroad cancer settlements cancer by avoiding smoking and limiting your drinking alcohol.

Barrett's esophagus is another factor that can increase your risk of esophageal cancer. This condition occurs when the tissue lining the esophagus gets replaced by tissue that appears more like the stomach's lining. This condition may necessitate that those suffering from this condition have their esophagus routinely examined for precancerous cells by undergoing regular endoscopies.

The International Agency for Research on Cancer recently classified the carcinogen acetaldehyde found in alcoholic beverages as group 1 (probably carcinogenic to humans). This change is due to a mutation in the ALDH2 enzyme, which increases acetaldehyde in blood, saliva, and breath after drinking. The study published in Cancer Epidemiology, Biomarkers & Prevention found that this variant was associated with a greater chance of developing esophageal carcinoma squamous cell.

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