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Chronic Lymphocytic Leukemia Lawsuit
Chronic lymphocytic leukemia (CLL) is the most common type of blood cancer among adults. It begins in cells that develop into specific kinds of white cells in the bone marrow, and spreads to the blood.
Certain people have higher risk factors than others, however having a risk factor does not guarantee that you'll be a victim of the disease.
Causes
The root cause of chronic lymphocytic leukemia isn't identified. It is caused when healthy white blood cells (lymphocytes) which are found in the bone marrow, begin to alter. These abnormal cells crowd out healthy blood cells and hinder the creation of new ones. They may also expand to lymph nodes as well as other organs.
The majority of people with CLL do not experience any symptoms until they receive diagnosed. They are diagnosed following an examination for a routine physical exam or as a result of a test done for another reason, when the doctor observes a significant number of white blood cells.
Untreated CLL could lead to anemia (low red blood cell counts) as well as a lower count of platelets (thrombocytopenia) and infections. A condition known as autoimmune hemolytic anemia can also occur when the disease fighting lymphocytes mistakenly destroy healthy red cells. Certain individuals with CLL also suffer from an illness called immune thrombocytopenia.
Researchers have discovered that having a first-degree relative who has had chronic lymphocyticleukemia makes an individual twice more likely to develop cancer. Other risk factors include age and being male, as well as exposure to the herbicide Agent Orange during the Vietnam War or other chemicals, such as glyphosate. Other health issues such as obesity or heart disease could increase a person's chance of developing the cancer.
Signs and symptoms
Many people with chronic lymphocytic leukemia don't have any symptoms when they are diagnosed. A doctor might discover that the patient is suffering from CLL when they run blood tests for an unrelated issue or perform a routine checkup. The CLL abnormal lymphocytes replace normal bone marrow blood-making cells. This can lead to a shortage of healthy white blood cells (leukopenia), a shortage of healthy blood platelets (thrombocytopenia) and anemia (low levels of red blood cells). The decreased number of normal blood cells increases the risk of infection.
CLL patients are at a greater risk than the average of developing other cancers, such as lung, skin cancer and cancer colon cancer. They also have a greater chance of being diagnosed with CLL develop into an aggressive form of the disease, namely diffuse large B-cell lymphoma.
Doctors classify chronic Lymphocytic Leukemia by the size of the tumor your body, as well as the other blood cell counts. It is also grouped into stages. In stage A, you have swelling lymph nodes in two regions of your body, but you don't suffer from anemia or low numbers of platelets. In stage B, you have lymph nodes that are enlarged and swollen, as well as the liver or spleen. However, you don't suffer from anemia and your platelet counts are normal. In stage C, you've swelling of the lymph nodes, low platelet counts and anemia.
Diagnosis
Many people suffering from chronic leukemia don't display any signs. The diagnosis is made after an examination of blood results shows the presence of too many white blood cells. The cancerous cells could crowd out healthy blood cells and make it difficult for the body to fight off infections and carry oxygen to tissues, manage bleeding and perform other vital functions.
NYU Langone doctors diagnose CLL by using sophisticated tests on tissue and blood. CLL affects the spongy substance in bones, also known as bone marrow, cancer which is where blood cells are made. The bone marrow makes lymphocytes, which are white blood cells that fight infections and other illnesses. In CLL the lymphocytes do not develop into healthy white blood cells and release into the bloodstream where they attack healthy tissues. This increases the risk of developing bacterial infections, viral infections and fungal infections.
Other signs include a feeling that you're always tired, swelling of lymph nodes in your neck armpits, groin, and armpits bleeding or bruising and an abnormally low blood platelet count (thrombocytopenia). Platelets are blood cells that assist in forming blood clots.
A lumbar puncture, also known as a spinal tap is used by doctors to check for indications of cancer spreading to the central nervous system (brain and the spinal cord). The procedure involves inserting needles into the spinal column to remove cerebrospinal fluid for examination under a microscop.
Treatment
The primary objectives of treatment is to bring the cancer to remission and to prevent it from progressing. Treatment options currently include oral medications that target specific proteins involved in the disease, for instance Bruton tyrosine kinase inhibitors (such as venetoclax) and next-generation monoclonal anti-CD20 antibodies (such as obinutuzumab).
A complete blood count differential counts white blood cell and flags abnormal or immature blood cells. The tests for blood chemistry measure substances like electrolytes (salts), sugars, proteins and glucose. A test called flow cytometry aids in identifying the type of leukemia cells, and determine the degree of their aggressiveness.
These tests and other tests will be utilized by your doctor to determine if have chronic leukemia. The test results help your doctor plan the best treatments. Your doctor will also search for signs of the cancer spreading, such as swelling of lymph nodes or signs such as fatigue. Your doctor might order an x-ray of your chest, which utilizes a beam of energy to take images inside your body.
If your cancer is in its early stages it is not necessary to seek treatment right away. Research has proven that treatment does not prolong lives for patients in this stage. Your doctor will be monitoring your condition closely and start treatment only when you start showing signs or symptoms, or the leukemia is beginning to grow.
Chronic lymphocytic leukemia (CLL) is the most common type of blood cancer among adults. It begins in cells that develop into specific kinds of white cells in the bone marrow, and spreads to the blood.
Certain people have higher risk factors than others, however having a risk factor does not guarantee that you'll be a victim of the disease.
Causes
The root cause of chronic lymphocytic leukemia isn't identified. It is caused when healthy white blood cells (lymphocytes) which are found in the bone marrow, begin to alter. These abnormal cells crowd out healthy blood cells and hinder the creation of new ones. They may also expand to lymph nodes as well as other organs.
The majority of people with CLL do not experience any symptoms until they receive diagnosed. They are diagnosed following an examination for a routine physical exam or as a result of a test done for another reason, when the doctor observes a significant number of white blood cells.
Untreated CLL could lead to anemia (low red blood cell counts) as well as a lower count of platelets (thrombocytopenia) and infections. A condition known as autoimmune hemolytic anemia can also occur when the disease fighting lymphocytes mistakenly destroy healthy red cells. Certain individuals with CLL also suffer from an illness called immune thrombocytopenia.
Researchers have discovered that having a first-degree relative who has had chronic lymphocyticleukemia makes an individual twice more likely to develop cancer. Other risk factors include age and being male, as well as exposure to the herbicide Agent Orange during the Vietnam War or other chemicals, such as glyphosate. Other health issues such as obesity or heart disease could increase a person's chance of developing the cancer.
Signs and symptoms
Many people with chronic lymphocytic leukemia don't have any symptoms when they are diagnosed. A doctor might discover that the patient is suffering from CLL when they run blood tests for an unrelated issue or perform a routine checkup. The CLL abnormal lymphocytes replace normal bone marrow blood-making cells. This can lead to a shortage of healthy white blood cells (leukopenia), a shortage of healthy blood platelets (thrombocytopenia) and anemia (low levels of red blood cells). The decreased number of normal blood cells increases the risk of infection.
CLL patients are at a greater risk than the average of developing other cancers, such as lung, skin cancer and cancer colon cancer. They also have a greater chance of being diagnosed with CLL develop into an aggressive form of the disease, namely diffuse large B-cell lymphoma.
Doctors classify chronic Lymphocytic Leukemia by the size of the tumor your body, as well as the other blood cell counts. It is also grouped into stages. In stage A, you have swelling lymph nodes in two regions of your body, but you don't suffer from anemia or low numbers of platelets. In stage B, you have lymph nodes that are enlarged and swollen, as well as the liver or spleen. However, you don't suffer from anemia and your platelet counts are normal. In stage C, you've swelling of the lymph nodes, low platelet counts and anemia.
Diagnosis
Many people suffering from chronic leukemia don't display any signs. The diagnosis is made after an examination of blood results shows the presence of too many white blood cells. The cancerous cells could crowd out healthy blood cells and make it difficult for the body to fight off infections and carry oxygen to tissues, manage bleeding and perform other vital functions.
NYU Langone doctors diagnose CLL by using sophisticated tests on tissue and blood. CLL affects the spongy substance in bones, also known as bone marrow, cancer which is where blood cells are made. The bone marrow makes lymphocytes, which are white blood cells that fight infections and other illnesses. In CLL the lymphocytes do not develop into healthy white blood cells and release into the bloodstream where they attack healthy tissues. This increases the risk of developing bacterial infections, viral infections and fungal infections.
Other signs include a feeling that you're always tired, swelling of lymph nodes in your neck armpits, groin, and armpits bleeding or bruising and an abnormally low blood platelet count (thrombocytopenia). Platelets are blood cells that assist in forming blood clots.
A lumbar puncture, also known as a spinal tap is used by doctors to check for indications of cancer spreading to the central nervous system (brain and the spinal cord). The procedure involves inserting needles into the spinal column to remove cerebrospinal fluid for examination under a microscop.
Treatment
The primary objectives of treatment is to bring the cancer to remission and to prevent it from progressing. Treatment options currently include oral medications that target specific proteins involved in the disease, for instance Bruton tyrosine kinase inhibitors (such as venetoclax) and next-generation monoclonal anti-CD20 antibodies (such as obinutuzumab).
A complete blood count differential counts white blood cell and flags abnormal or immature blood cells. The tests for blood chemistry measure substances like electrolytes (salts), sugars, proteins and glucose. A test called flow cytometry aids in identifying the type of leukemia cells, and determine the degree of their aggressiveness.
These tests and other tests will be utilized by your doctor to determine if have chronic leukemia. The test results help your doctor plan the best treatments. Your doctor will also search for signs of the cancer spreading, such as swelling of lymph nodes or signs such as fatigue. Your doctor might order an x-ray of your chest, which utilizes a beam of energy to take images inside your body.
If your cancer is in its early stages it is not necessary to seek treatment right away. Research has proven that treatment does not prolong lives for patients in this stage. Your doctor will be monitoring your condition closely and start treatment only when you start showing signs or symptoms, or the leukemia is beginning to grow.
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